Both Orthovisc and Supartz FX are fabricated via substances derived from the fleshy growths on the heads of roosters and chickens, known as “combs”. This presents contraindications for those who are allergic to egg products, feathers, or avian proteins. Following the procedure, pain and swelling is possible, but only in short duration. Injections, while still a surgical procedure, are low-risk and patients are often eager to receive them. However, it is not a cure, though, a response can last from nine to twelve months.